SRMS CET, Bareilly boasts a vibrant community of distinguished faculties passionate about nurturing the minds of our talented students. Let’s hear out loud to its esteemed faculties in our exclusive #FacultySpeaks Column, whose pioneering researches & patents not only provide valuable insights into tuberculosis treatment and drug enhancement, but also lay foundation for further discoveries in the realm of medicine.
Joining the brigade, Dr Arti Gupta, Director Pharmacy and Dr Jitendra Singh Yadav, Professor of Pharmacy at SRMS CET have taken a remarkable stride in medicinal research. The duo’s groundbreaking research work has resulted in the publication of two patents titled ‘SYNTHESIS OF CITRATE CAPPED URSOLIC ACID GOLD NANOPARTICLES AND USE’ & ‘TPGS BASED STABILISED MIXED MICELLAR SYSTEM TO IMPROVE SOLUBILITY AND PERMEABILITY OF OLEANOLIC ACID’ that unleashes promising opportunities for medical advancements.
Speaking about PATENT-1 titled ‘Synthesis of Citrate Capped Ursolic Acid Gold Nanoparticles and Use’, which is a revolutionary & novel approach to combat tuberculosis, Dr Arti Gupta shares, “Through meticulous experimentation by employing a chemical reduction method, we’ve synthesized citrate capped ursolic acid gold nanoparticles comprising chloroauric acid, urosolic acid & trisodium citrate, demonstrating their efficacy in treating this persistent disease. Rigorously evaluated through various techniques like Particle size, FTIR, DSC, TEM, XRD, PDI, Zeta potential & % Drug Diffusion study, these nanoparticles exhibit immense potential in tuberculosis treatment.”
On PATENT-2 titled ‘TPGS Based Stabilized Mixed Micellar System to Improve Solubility and Permeability of Oleanolic Acid’, Dr Jitendra Singh Yadav remarks, “The invention introduces a mixed micelle comprising D-a-tocopheryl polyethylene glycol & a block polymer. Specifically, the invention revolves around TPGS-based stabilized mixed micellar system, which boosts solubility & permeability of oleanolic acid—an essential compound with therapeutic potential, helpful in treating skin infections.